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17 Apr

MedPage is a far left medical page that will sometimes get it right. Well I found this article interesting. Here's bits and pieces. The whole article can be found here.

Fully vaccinated individuals were more likely to have a breakthrough COVID-19 infection if they had a psychiatric disorder diagnosis, a retrospective study of Veterans Affairs data found. 

In a fully adjusted model, any psychiatric disorder was associated with a 3% higher risk for a breakthrough COVID infection (adjusted relative risk [aRR] 1.03, 95% CI 1.01-1.05, P<0.001) though certain diagnoses appeared to carry far higher risk, reported Aoife O'Donovan, PhD, of the University of California San Francisco, and colleagues. 

"Individual psychiatric disorders were associated with a 3% to 16% increased incidence of breakthrough infection in our sample, which is comparable to the 7% to 23% increased incidence of breakthrough infection that we observed for physical comorbidities (e.g., cancer, kidney disease, and cardiovascular disease)," the group wrote in JAMA Network Open

But even in the younger group, anxiety disorder, adjustment disorder, and substance use disorder were each associated with an increased risk for breakthrough infection. "Mental and physical health are intricately intertwined," said O'Donovan. "It behooves us to increase the resources available for mental health during the pandemic." 

For their study, O'Donovan and colleagues examined electronic health record data on 263,697 fully vaccinated veterans from Department of Veterans Affairs databases. They included individuals who were tested at least once for SARS-CoV-2 infection from February 2020 to November 2021, but who did not have a SARS-CoV-2 infection prior to becoming vaccinated. Overall, 15% developed a breakthrough infection during the study period. 

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